Ali Bashashati

Director of AI Research at BC Ovarian Cancer Program (OVCARE), Assistant Professor in Biomedical Engineering & Pathology
  • PhD in Electrical & Computer Engineering, University of British Columbia, Canada
  • MSc in Biomedical Engineering, Amirkabir University of Technology, Iran
  • BSc in Electrical Engineering, Sharif University of Technology, Iran

  • I received my B.Sc. degree in Electrical Engineering from Sharif University of Technology (SUT), Iran in 2000, the M.Sc. degree in Biomedical Engineering from Amirkabir University of Technology (Tehran polytechnic), Iran in 2002, and the Ph.D. degree in Electrical & Computer Engineering from the University of British Columbia, Canada in 2007. I am currently the Director of artificial intelligence (AI) Research in the Ovarian Cancer Research Program (OVCARE) of the BC Cancer/UBC as well as a faculty member in the Department of Pathology & Laboratory Medicine and the School of Biomedical Engineering (SBME). My research area lies at the interface between computational, engineering and biomedical sciences. I am interested in developing AI/machine learning, statistical and signal processing algorithms and software infrastructure to combine various sources of omics and imaging data with major emphasis on genomics and digital pathology in cancer.


    Synthesis of diagnostic quality cancer pathology images

    Synthesis of high resolution glioma pathology images using generative adversarial networks

    Classification of Epithelial Ovarian Carcinoma Whole-Slide Pathology Images Using Deep Transfer Learning

    TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma

    Endometrial Cancer Molecular Risk Stratification is Equally Prognostic for Endometrioid Ovarian Carcinoma

    The coming 15~years in gynaecological pathology: digitisation, artificial intelligence, and new technologies


    Molecular profiling and molecular classification of endometrioid ovarian carcinomas

    Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia

    Abstract 3480:TMEM30Aloss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma

    Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically

    Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation

    Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition

    Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models

    Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma

    The Double-Hit Gene Expression Signature Defines a Clinically and Biologically Distinct Subgroup within GCB-DLBCL

    Somatic PRAME Deletions Are Associated with Decreased Immunogenicity, Apoptosis Resistance and Poor Outcomes in Diffuse Large B-Cell Lymphoma

    Abstract B22: Capturing L1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers as a way to track tumor development

    Abstract PR13: TERT is frequently mutated in adult-type granulosa cell tumors of the ovary compared to other malignant sex cord-stromal tumors

    Abstract B22: Capturing L1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers as a way to track tumor development

    TERT promoter mutation in adult granulosa cell tumor of the ovary

    Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer

    Integrated single-nucleotide and structural variation signatures of DNA-repair deficient human cancers

    Genetic Characterization and Clinical Impact of Loss of MHC Class I and II Expression in De Novo Diffuse Large B-Cell Lymphoma

    LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers

    The driver landscape of sporadic chordoma

    Abstract 3381: TERT promoter mutation in granulosa cell tumours of the ovary: Prevalence and prognostic significance

    Abstract 2445: Integrative genetic analysis identifies therapeutic relevance of cell of origin-specific genetic alterations in diffuse large B-cell lymphoma

    Kronos: a workflow assembler for genome analytics and informatics

    CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion


    Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes

    Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell-of-origin–specific clinical impact

    The interface of malignant and immunologic clonal dynamics in high-grade serous ovarian cancer

    Neural Network Conditional Random Fields for Self-Paced Brain Computer Interfaces

    Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study

    Targeted Sequencing Reveals Novel Gene Mutations Associated with Transformation and Early Progression in Follicular Lymphoma

    Divergent Modes of Tumor Evolution Underlie Histological Transformation and Early Progression of Follicular Lymphoma

    Frequent Genetic Alterations of PI3K-AKT Pathway and Their Clinical Significance in Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma

    Robust high-performance nanoliter-volume single-cell multiple displacement amplification on planar substrates

    Abstract LB-324: Genomic consequences of aberrant DNA repair stratify ovarian cancer histotypes

    Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer

    Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality

    Bayesian optimization of BCI parameters

    User-customized brain computer interfaces using Bayesian optimization

    Abstract PR07: Synchronous ovarian and endometrial carcinomas: The case for pseudo-metastasis.

    The genomic landscape of epithelioid sarcoma cell lines and tumours

    Hidden Markov Support Vector Machines for Self-Paced Brain Computer Interfaces

    Systematic analysis of somatic mutations impacting gene expression in 12 tumour types

    Abstract AS18: The somatic mutational landscape of endometriosis associated ovarian cancers and precursor lesions

    Comparing Different Classifiers in Sensory Motor Brain Computer Interfaces

    Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden

    An RCOR1 loss–associated gene expression signature identifies a prognostically significant DLBCL subgroup

    Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution

    TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

    Abstract LB-312: The somatic mutational landscape of ovarian clear cell carcinoma and its precursor lesions

    Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

    DriverNet: uncovering the impact of somatic driver mutations on transcriptional networks in cancer

    Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer

    The genomic and transcriptomic architecture of 2, 000 breast tumours reveals novel subgroups

    The clonal and mutational evolution spectrum of primary triple-negative breast cancers

    B Cells With High Side Scatter Parameter by Flow Cytometry Correlate With Inferior Survival in Diffuse Large B-Cell Lymphoma

    JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data

    Feature-based classifiers for somatic mutation detection in tumour–normal paired sequencing data

    Automated Analysis of Multidimensional Flow Cytometry Data Improves Diagnostic Accuracy Between Mantle Cell Lymphoma and Small Lymphocytic Lymphoma


    A Random Forests-based approach for estimating depth of human body gestures using a single video camera

    Random forests-based 2D-to-3D video conversion

    Pairwise network mechanisms in the host signaling response to coxsackievirus B3 infection

    Per-channel basis normalization methods for flow cytometry data